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Bio, Work & Ideas
Conference affiliation: Machine Learning Scientist · Morgan Stanley · 2026
Brendan Rappazzo is an applied researcher at Prime Intellect developing open models, reinforcement-learning methods, and autonomous research systems. Previously a machine-learning scientist at Morgan Stanley, he helped build AlphaLab, a multi-agent platform for quantitative research that treats rigorous evaluation as the foundation of useful automation.
Rappazzo studied bioengineering and biomedical engineering at the University of Maryland, College Park, before earning a master’s degree and doctorate at Cornell University. Working with Carla Gomes on computational sustainability, he contributed to Phase-Mapper, an award-winning materials-discovery system, and developed computer-vision methods for measuring eelgrass disease. His research also addressed hydropower planning in the Amazon.
His subsequent work investigated how machine-learning systems recognize and correct their own mistakes. He coauthored Critic Loss for Image Classification, which uses a learned correctness critic to improve classification and calibration with limited labeled data; the research received ICMLA’s 2024 best-paper award. He also coauthored GEM-RAG, a retrieval architecture built around graph-structured memories and higher-level summaries.
After completing his doctorate, Rappazzo joined Morgan Stanley’s machine-learning research group. There, AlphaLab combined frontier language models with domain research, evaluation construction, and large-scale experimentation. Its strategist proposes hypotheses while worker agents implement models, launch Slurm-managed compute jobs, inspect training results, and refine subsequent experiments; human researchers can intervene and compare candidates against held-out data. His AI Engineer World’s Fair presentation detailed applications spanning time-series forecasting, CUDA kernels, and language-model training.
In August 2026, Rappazzo left Morgan Stanley and joined Prime Intellect’s applied research team, advocating open-source intelligence that lets individuals and organizations train and control their own models.